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Clinical Studies

Learn more about studies on gastrointestinal, urinary, liver, behaviour and skin health in dogs and cats. 

Protexin Veterinary is committed to a programme of continuous research and development, and has commissioned independent research that has been central to the growing scientific awareness that probiotics can make an effective contribution to good health.

The studies presented here explore the efficacy and relevance of several of our products designed to aid in the management of gastrointestinal, urinary, liver, skin diseases and behaviour in dogs and cats.

Magnifying glass looking at an epidermal hair

DermalEase: Topical treatment with sphingolipids and glycosaminoglycans for canine atopic dermatitis

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S-adenosylmethionine (SAMe) in a feline acetaminophen model of oxidative injury

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Measurement of the S-adenosyl methionine (SAMe) content in a range of commercial veterinary SAMe supplements

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Denamarin: Prospective randomized clinical trial assessing the efficacy of Denamarin for prevention of CCNU-induced hepatopathy in tumor-bearing dogs

A cat and a dog sleeping near each other

Effect of alpha-casozepine on anxiety in cats

A cat and a dog sleeping near each other

Effect of alpha-casozepine versus selegiline hydrochloride on anxiety disorders in dogs

A cat and a dog sleeping near each other

Gut-Brain Axis Impact on Canine Anxiety Disorders: New Challenges for Behavioural Veterinary Medicine

Urinary Solutions

Effects of oral administration of N-acetyl-d-glucosamine on plasma and urine concentrations of glycosaminoglycans in cats with idiopathic cystitis

Urinary Solutions

Standardized cranberry tablet inhibits uropathogenic bacterial adhesion in canine urine

Urinary Solutions

Effect of dietary intake of L-Tryptophan supplementation on multi-housed cats presenting stress related behaviours

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Cobalaplex/ Cobalazorb: Efficacy and tolerance of oral versus parenteral cyanocobalamin supplement in hypocobalaminaemic dogs with chronic enteropathy

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Pro-Kolin Enterogenic: Effects of concurrent ronidazole and probiotic therapy in cats with tritrichomonas foetus-associated diarrhoea

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Synbiotic DC: Efficacy of a probiotic-prebiotic supplement on incidence of diarrhoea in a dog shelter

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Acid stability of Protexin probiotic micro-organisms

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Efficacy of an orally administered anti-diarrheal probiotic paste (Pro-Kolin Advanced) in dogs with acute diarrhoea