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Urinary Detailer References

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  • Howell AB, Griffin DW, Whalen MO. Standardized cranberry tablet inhibits uropathogenic bacterial adhesion in canine urine. Poster presented at Berry Health Benefits Symposium, 2011.
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  • Sun J, Marais JP, Khoo C, et al. Cranberry (Vaccinium macrocarpon) oligosaccharides decrease biofilm formation by uropathogenic Escherichia coli. J Funct Foods 2015; 17: 235-42.
  • Foo LY, Lu Y, Howell AB, Vorsa N. The structure of cranberry proanthocyanidins which inhibit adherence of uropathogenic P-fimbriated Escherichia coli in vitro. Phytochemistry 2000; 54(2): 173-81.
  • Di Martino P, Agniel R, David K, et al. Reduction of Escherichia coli adherence to uroepithelial bladder cells after consumption of cranberry juice: a double-blind randomized placebo-controlled cross-over trial. World J Urol 2006; 24: 21-7.
  • Gupta K, Chou MY, Howell A, Wobbe C, Grady R, Stapleton AE. Cranberry products inhibit adherence of P-fimbriated Escherichia coli to primary cultured bladder and vaginal epithelial cells. J Urol 2007; 177(6): 2357-60.
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  • Singh I, Gautam LK, Kaur IR. Effect of oral cranberry extract (standardized proanthocyanidin-A) in patients with recurrent UTI by pathogenic E. coli: a randomized placebo-controlled clinical research study. Int Urol Nephrol 2016; 48: 1379-86.
  • Nicolosi D, Tempera G, Genovese C, Furneri PM. Anti-adhesion activity of A2-type proanthocyanidins (a cranberry major component) on uropathogenic E. coli and P. mirabilis strains. Antibiotics 2014; 3(2): 143-54.
  • EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP). Scientific opinion on the safety and efficacy of Oralin®(Enterococcus faecium) as a feed additive for calves for rearing, piglets, chickens for fattening, turkeys for fattening and dogs. EFSA J 2014; 12(6): 3727.
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  • Quinto EJ, Jiménez P, Caro I, Tejero J, Mateo J, Girbés T. Probiotic lactic acid bacteria: a review. Food Nutr Sci 2014; 5(18): 1765.
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  • Reid G, Bruce AW. Probiotics to prevent urinary tract infections: the rationale and evidence. World J Urol 2006; 24: 28-32.
  • Jana UK, Suryawanshi RK, Prajapati BP, Kango N. Prebiotic mannooligosaccharides: synthesis, characterization and bioactive properties. Food Chem 2021; 342: 128328.
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  • Levi YL, Novais GS, Dias RB, et al. Effects of the prebiotic mannan oligosaccharide on the experimental periodontitis in rats. J Clin Periodontol 2018; 45(9): 1078-89.
  • Jahanian R, Ashnagar M. Effect of dietary supplementation of mannan-oligosaccharides on performance, blood metabolites, ileal nutrient digestibility, and gut microflora in Escherichia coli-challenged laying hens. Poultry Sci 2015; 94(9): 2165-72.
  • Caldas AP, Coelho OG, Bressan J. Cranberry antioxidant power on oxidative stress, inflammation and mitochondrial damage. Int J Food Prop 2018; 21(1): 582-92.
  • Zeng YX, Wang S, Wei L, Cui YY, Chen YH. Proanthocyanidins: components, pharmacokinetics and biomedical properties. Am J Chin Med 2020; 48(04): 813-69.
  • Howell AB, Botto H, Combescure C, et al. Dosage effect on uropathogenic Escherichia coli anti-adhesion activity in urine following consumption of cranberry powder standardized for proanthocyanidin content: a multicentric randomized double blind study. BMC Infect Dis 2010; 10: 94.
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  • Parsons CL, Mulholland SG, Anwar H. Antibacterial activity of bladder surface mucin duplicated by exogenous glycosaminoglycan (heparin). Infect Immun 1979; 24(2): 552-7.
  • Parsons CL, Pollen JJ, Anwar HA, Stauffer CH, Schmidt JD. Antibacterial activity of bladder surface mucin duplicated in the rabbit bladder by exogenous glycosaminoglycan (sodium pentosanpolysulfate). Infect Immun 1980; 27(3): 876-81.
  • Salazar AM, Neugent ML, De Nisco NJ, Mysorekar IU. Gut-bladder axis enters the stage: implication for recurrent urinary tract infections. Cell Host Microbe 2022; 30(8): 1066-9.
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  • Data on file – acid stability
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  • Jalanka J, Major G, Murray K, et al. The effect of psyllium husk on intestinal microbiota in constipated patients and healthy controls. Int J Mol Sci 2019; 20(2): 433.