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ANZ Pro-Kolin+ References

  1. EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP). Scientific opinion on the safety and efficacy of Oralin®(Enterococcus faecium) as a feed additive for calves for rearing, piglets, chickens for fattening, turkeys for fattening and dogs. EFSA J 2014; 12(6): 3727
  2. EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP). Scientific opinion on the safety and efficacy of Oralin®(Enterococcus faecium) when used as a feed additive for cats. EFSA J 2014; 12(3): 3602.
  3. Data on file – acid stability
  4. Akimoto M, Nagahata N, Furuya A, Fukushima K, Higuchi S, Suwa T. Gastric pH profiles of beagle dogs and their use as an alternative to human testing. Eur J Pharm Biopharm 2000; 49(2): 99-102.
  5. Sagawa K, Li F, Liese R, Sutton SC. Fed and fasted gastric pH and gastric residence time in conscious beagle dogs. J Pharm Sci 2009; 98(7): 2494-2500.
  6. Lui CY, Amidon GL, Berardi RR, Fleisher D, Youngberg C, Dressman JB. Comparison of gastrointestinal pH in dogs and humans: implications on the use of the beagle dog as a model for oral absorption in humans. J Pharm Sci 198; 75(3): 271-274. 
  7. Slavin J. Fiber and prebiotics: mechanisms and health benefits. Nutrients 2013; 5(4): 1417-1435.
  8. Tan J, McKenzie C, Potamitis M, Thorburn AN, Mackay CR, Macia L. The role of short-chain fatty acids in health and disease. Adv Immunol 2014; 121: 91-119.
  9. Jalanka J, Major G, Murray K, et al. The effect of psyllium husk on intestinal microbiota in constipated patients and healthy controls. Int J Mol Sci 2019; 20(2): 433.
  10. Marzorati M, Qin B, Hildebrand F, et al. Addition of acacia gum to a FOS/inulin blend improves its fermentation profile in the Simulator of the Human Intestinal Microbial Ecosystem (SHIME®). J Funct Foods 2015; 16: 211-222.
  11. Cherbut C, Michel C, Raison V, Kravtchenko T, Severine M. Acacia gum is a bifidogenic dietary fibre with high digestive tolerance in healthy humans. Microb Ecol Health Dis 2003; 15(1): 43-50.
  12. Gibson GR. Dietary modulation of the human gut microflora using the prebiotics oligofructose and inulin. J Nutr 1999; 129(7): 1438S-41S.
  13. Adam CL, Williams PA, Garden KE, Thomson LM, Ross AW. Dose-dependent effects of a soluble dietary fibre (pectin) on food intake, adiposity, gut hypertrophy and gut satiety hormone secretion in rats. PLoS One 2015; 10(1): e0115438.
  14. Wong TW, Colombo G, Sonvico F. Pectin matrix as oral drug delivery vehicle for colon cancer treatment. AAPS PharmSciTech 2011; 12: 201-214.
  15. Bender C, Stoll D, Huch M, et al. Time-dependent fermentation of different structural units of commercial pectins with intestinal bacteria. Carbohydr Polym 2023; 308: 120642.
  16. Villamiel M. What we know about pectin ES Food & Agroforestry 2021; 3:27-30.
  17. Blanco-Pérez F, Steigerwald H, Schülke S, Vieths S, Toda M, Scheurer S. The dietary fiber pectin: health benefits and potential for the treatment of allergies by modulation of gut microbiota. Curr Allergy Asthma Rep 2021; 21: 1-9.
  18. Biagi G, Cipollini I, Grandi M, Zaghini G. Influence of some potential prebiotics and fibre-rich foodstuffs on composition and activity of canine intestinal microbiota. Anim Feed Sci Technol 2010; 159(1-2): 50-58.
  19. Barry KA, Wojcicki BJ, Middelbos IS, Vester BM, Swanson KS, Fahey Jr GC. Dietary cellulose, fructooligosaccharides, and pectin modify fecal protein catabolites and microbial populations in adult cats. J Anim Sci 2010; 88(9): 2978-2987.
  20. Carretero MI, Pozo M. Clay and non-clay minerals in the pharmaceutical and cosmetic industries. Part II. Active ingredients. App. Clay Sci. 2010; 47: 171-181.